Custom Enzymes and Inhibitors
Selleck Chemical LLC Dutasteride 10mg 164656-23-9 GI198745, GG-745
Dutasteride (GI198745, GG-745) is a dual 5-? reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT). *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Foretinib (GSK1363089) 50mg 849217-64-7 EXEL-2880,XL-880
Foretinib (GSK1363089, EXEL-2880, XL-880) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met (c-Met) and KDR with IC50 of 0.4 nM and 0.9 nM in cell-free assays. Less potent against Ron, Flt-1/3/4, Kit (c-Kit), PDGFR?/? and Tie-2, and little activity to FGFR1 and EGFR. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Roflumilast 5mg 162401-32-3 APTA 2217, B9302-107, BY 217, BYK 20869
Roflumilast (APTA 2217, B9302-107, BY 217, BYK 20869) is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM in a cell-free assay. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Lapatinib (GW-572016) Ditosylate 100mg 388082-77-7
Lapatinib (GW-572016) Ditosylate is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences Ubiquitin aldehyde (recombinant) (50 µg)
High purity inhibitor of deubiquitinylating enzymes (DUBs). Synthetically modified recombinant ubiquitin. The modification of the C-terminal glycine carboxyl into an aldehyde results in a potent, highly specific inhibitor of all ubiquitin deconjugating enzymes, including ubiquitin C-terminal hydrolases (UCHs), ubiquitin-specific proteases (USPs) and deubiquitinylating enzymes (DUBs). Alternative name: Ub-H. MW: 8.5kDa. Purity: ≥95% (HPLC). Sequence Recombinant Ubiquitin (corresponding to UniProt sequence P62988). The C-terminal glycine carboxyl is synthetically modified to an aldehyde. Formulation: Liquid. In aqueous solution containing 0.15M HCl. Source: Produced in E.coli. UniProt: P0CG47 (UBB), P0CG48 (UBC), P62979 (RPS27A), P62987 (UBA52). Handling: Do not neutralise until immediateley prior to use. Do not lyophilize. Avoid presence of amino-containing compounds. Soluble and stable in aqueous solution at pH <7.0. Long Term Storage: +4°C
Sigma Organic Chemistry trans-2-Phenylcyclopropyl isocyanate | 5G | 63009-74-5 | MFCD00001273
CAS #: 63009-74-5
MDL #: MFCD00001273
Purity: >90%
UNSPSC Code: 12352100
Molecular Weight: 159.18
Medchemexpress LLC HY-103353 5mg Medchemexpress, SID 26681509 CAS:958772-66-2 Purity:>98%
Medchemexpress, HY-103353 5mg SID 26681509 CAS:958772-66-2 SID 26681509 is a potent, reversible, competitive, and selective inhibitor of human cathepsin L with an IC50 of 56 nM. SID 26681509 inhibits in vitro propagation of malaria parasite Plasmodium falciparum and inhibits Leishmania major with IC50s of 15.4 μM and 12.5 μM, respectively. SID 26681509 shows no inhibitory activity against cathepsin G. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-107613 10mg Medchemexpress, R 59-022 CAS:93076-89-2 Purity:>98%
Medchemexpress, HY-107613 10mg R 59-022 CAS:93076-89-2 R 59-022 (DKGI-I) is a diacylglycerol kinase inhibitor (IC50=2.8 μM). R 59-022 is a 5-HTR antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils[3][4]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Meridian Life Science Tru Block, 0.1 g
HAMA Blocker against Immunoassay Interference - actively blocks Heterophilic Antibody (HA) interference in immunoassays including, but not limited to, Human Anti-Mouse Antibody (HAMA) interference.
Selleck Chemical LLC BI 2536 10mM/1mL 755038-02-9
BI-2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM in a cell-free assay. BI-2536 inhibits Bromodomain 4 (BRD4) with Kd of 37 nM and potently suppresses c-Myc expression. BI-2536 induces apoptosis and attenuates autophagy. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC PD98059 10mM/1mL 167869-21-8
PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 ?M in a cell-free assay, specifically inhibits MEK-1-mediated activation of MAPK; does not directly inhibit ERK1 or ERK2. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR) and functions as an AHR antagonist. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Raltitrexed 10mg 112887-68-0 ZD-1694
Raltitrexed (ZD-1694) is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Lamivudine 10mg 134678-17-4 GR109714X
Lamivudine (GR109714X) is a potent nucleoside analog reverse transcriptase inhibitor, used for treatment of chronic HBV and HIV/AIDS. It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase. *For Research & Development use only. Product is not intended for drug, household, or human consumption.